Bioavailability and Lag¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
Name: | biolag_abs_both |
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Title: | Bioavailability and Lag |
Author: | Wright Dose Ltd |
Abstract: |
One compartment model absorption dosing with bioavailability and lag parameters.
Keywords: | identifiability; bioavailability; lag |
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Input Script: | biolag_abs_both_tut.pyml |
Diagram: |
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[ANOISE_STD] = 1.0000
f[BIO] = 0.5830
f[LAG] = 5.0000
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[ANOISE_STD] = 5.0000
f[BIO] = 0.8000
f[LAG] = 1.0000
Outputs¶
Generating and Fitting Summaries¶
- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)
Fitted f[X] values¶
f[KA] = 1.0000
f[CL] = 1.4961
f[V] = 9.1492
f[ANOISE_STD] = 0.8936
f[BIO] = 0.2861
f[LAG] = 8.9095
Plots¶
Comparison¶
True objective value¶
44.2050
Final fitted objective value¶
38.7523
Compare Main f[X]¶
Name | Initial | Fitted | True | Prop. Error | Abs. Error |
---|---|---|---|---|---|
f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
f[CL] | 1 | 1.5 | 3 | 50.13% | 1.50e+00 |
f[V] | 15 | 9.15 | 20 | 54.25% | 1.09e+01 |
f[BIO] | 0.8 | 0.286 | 0.583 | 50.92% | 2.97e-01 |
f[LAG] | 1 | 8.91 | 5 | 78.19% | 3.91e+00 |
Compare Noise f[X]¶
Name | Initial | Fitted | True | Prop. Error | Abs. Error |
---|---|---|---|---|---|
f[ANOISE_STD] | 5 | 0.894 | 1 | 10.64% | 1.06e-01 |
Compare Variance f[X]¶
No Variance f[X] values to compare.