.. _abbreviations:

Abbreviations
================

Throughout this book we use commonly found abbreviations in |pkpd|, some of
which are given below for convenience.


.. glossary::
    :sorted:
    
    FOCE
        :term:`first order conditional estimation`
    
    IMP
        :term:`importance sampling`
    
    ITS
        :term:`iterative two stage`
    
    JOE
        :term:`joint optimisation and estimation`
    
    ND
        :term:`none derivative estimation`
    
    LAPLACE
        :term:`Laplace approximation`
    
    SAEM
        :term:`stochastic approximation expectation maximisation`
        
    OBJV
        :term:`objective function` value
    
    ODEs
        :term:`ordinary differential equations`

    PK/PD
        Pharmacokinetic/Pharmacodynamic 
            
    TSLD
        Time since last dose
            
    VPC 
        :term:`visual predictive check`
  
    wrt 
        With respect to - usually defines rate of change variable in an |ode|
        
    IV 
        Intra-venous, |ie| injected directly into a vein
