Flip Flop tutorial with low initial estimates of KA, V and CL

[Generated automatically as a Generation summary]

Model Description

Name:: flip_flop_good
Title:: Flip Flop tutorial with low initial estimates of KA, V and CL
Author:: PoPy for PK/PD
Abstract:

One compartment model with a depot leading into a central compartment.

Here initial values of KE, KA, V are close to the true values, so we get a good fit near the true global minima.

Keywords:: flip flop; dep_one_cmp_k; one compartment model; good start values
Input Script:: flip_flop_good_gen.pyml
Diagram:

Outputs

Population simulated (sim) plots

indOBS_vs_TIME

Generated parameter .csv files

Fixed Effects:: fx_params.csv (gen)
Random Effects:: rx_params.csv (gen)
Model params:: mx_params.csv (gen)
State values:: sx_params.csv (gen)
Predictions:: px_params.csv (gen)
Observations:: synthetic_data.csv (gen)

Inputs

True f[X] values (for simulation)

f[KA] = 0.1500
f[KE] = 0.3000
f[ANOISE_STD] = 1.0000