Linear PD model
[Generated automatically as a Tutorial summary]
Model Description
- Name:
linear_pd_pop
- Title:
Linear PD model
- Author:
PoPy for PK/PD
- Abstract:
A simple (i.e. no PD compartments) Linear PD Model.
Model consists of a baseline which increases linearly with concentration.
- Keywords:
pd; linear; one compartment model
- Input Script:
- Diagram:
Comparison
True objective value
185.2839
Final fitted objective value
178.3795
Compare Main f[X]
Name |
Initial |
Fitted |
True |
Abs. Error |
Prop. Error |
|---|---|---|---|---|---|
f[BL] |
15 |
9.86 |
10 |
1.37e-01 |
1.37% |
f[SLOPE] |
0.5 |
1.04 |
1 |
3.93e-02 |
3.93% |
Compare Noise f[X]
Name |
Initial |
Fitted |
True |
Abs. Error |
Prop. Error |
|---|---|---|---|---|---|
f[PNOISE] |
0.03 |
0.0148 |
0.01 |
4.81e-03 |
48.09% |
f[ANOISE] |
0.2 |
0.436 |
0.5 |
6.36e-02 |
12.72% |
Compare Variance f[X]
Name |
Initial |
Fitted |
True |
Abs. Error |
Prop. Error |
|---|---|---|---|---|---|
f[BL_isv] |
0.1 |
0.0537 |
0.05 |
3.72e-03 |
7.44% |
f[BL_isv;SLOPE_isv] |
0 |
0.00616 |
0 |
6.16e-03 |
inf |
f[SLOPE_isv;BL_isv] |
0 |
0.00616 |
0 |
6.16e-03 |
inf |
f[SLOPE_isv] |
0.05 |
0.0403 |
0.03 |
1.03e-02 |
34.20% |
Outputs
Fitted f[X] values (after fitting)
f[BL] = 9.8634
f[SLOPE] = 1.0393
f[PNOISE] = 0.0148
f[ANOISE] = 0.4364
f[BL_isv,SLOPE_isv] = [
[ 0.0537, 0.0062 ],
[ 0.0062, 0.0403 ],
]
Generated data .csv file
- Synthetic Data:
Gen and Fit Summaries
Gen: Linear PD model (gen)
Fit: Linear PD model (fit)
Inputs
True f[X] values (for simulation)
f[BL] = 10.0000
f[SLOPE] = 1.0000
f[PNOISE] = 0.0100
f[ANOISE] = 0.5000
f[BL_isv,SLOPE_isv] = [
[ 0.0500, 0.0000 ],
[ 0.0000, 0.0300 ],
]
Starting f[X] values (before fitting)
f[BL] = 15.0000
f[SLOPE] = 0.5000
f[PNOISE] = 0.0300
f[ANOISE] = 0.2000
f[BL_isv,SLOPE_isv] = [
[ 0.1000, 0.0000 ],
[ 0.0000, 0.0500 ],
]