Throughout this book we use commonly found abbreviations in PK/PD, some of which are given below for convenience.
first order conditional estimation
importance sampling
iterative two stage
Intra-venous, i.e. injected directly into a vein
joint optimisation and estimation
Laplace approximation
none derivative estimation
objective function value
ordinary differential equations
Pharmacokinetic/Pharmacodynamic
stochastic approximation expectation maximisation
Time since last dose
visual predictive check
With respect to - usually defines rate of change variable in an ordinary differential equation