Validation Examples

The validation examples are often taken from the publicly available DDMoRe repository. Typically these are a Nonmem control file and Nonmem data file that together illustrate fitting a PK/PD model.

You can see the validation examples supplied with PoPy in the c:\PoPy\validation folder.

Each subdirectory contains a ‘readme.txt’ file that gives a brief overview of the example and how it was created from the DDMoRe equivalent.

Table 57 lists each of the models in this folder:-

Table 57 Validation Models

Name

Summary

Link

Citation

ddmore0061

Combined bolus + infusion PK model.

DDMoRe: 0061

[Harling2015]

ddmore0093

Circadian function with covariates.

DDMoRe: 0093

[Cheung2015]

ddmore0215

Markov and dropout hazard.

DDMoRe: 0215

[Girard2012]

ddmore0238

PopPK with infusion dosing + IOV.

DDMoRe: 0238

[Germovsek2017]