One Compartment Model with Absorption and no inter-occasion Variance f[CL_iov]=0¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_iov_naive |
|---|---|
| Title: | One Compartment Model with Absorption and no inter-occasion Variance f[CL_iov]=0 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_iov] is not estimated it is set to zero.
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | dep_one_cmp_cl_iov_naive.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[PNOISE_STD] = 0.1
f[ANOISE_STD] = 0.05
f[CL_isv] = 0.2
f[CL_iov] = 0.1
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[PNOISE_STD] = 0.2
f[ANOISE_STD] = 0.2
f[CL_isv] = 0.01
f[CL_iov] = 0
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1
f[CL] = 2.1462
f[V] = 22.086
f[PNOISE_STD] = 0.46359
f[ANOISE_STD] = 0.061732
f[CL_isv] = 4.2967
f[CL_iov] = 0
Plots¶
Comparison¶
True objective value¶
242.737153435
Final fitted objective value¶
-163.412466343
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 2.15 | 3 | 28.46% | 8.54e-01 |
| f[V] | 15 | 22.1 | 20 | 10.43% | 2.09e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.464 | 0.1 | 363.59% | 3.64e-01 |
| f[ANOISE_STD] | 0.2 | 0.0617 | 0.05 | 23.46% | 1.17e-02 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 4.3 | 0.2 | 2048.35% | 4.10e+00 |