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First order absorption model with peripheral compartment

[Generated automatically as a Generation summary]

Inputs

Description

Name:builtin_gen_example
Title:First order absorption model with peripheral compartment
Author:J.R. Hartley
Abstract:
A two compartment PK model with bolus dose and
first order absorption, similar to a Nonmem advan4trans4 model.
Keywords:generating; pk; advan4; dep_two_cmp; first order
Input Script:builtin_gen_example.pyml
Diagram:

True f[X] values

f[KA] = 0.2000
f[CL] = 2.0000
f[V1] = 50.0000
f[Q] = 1.0000
f[V2] = 80.0000
f[KA_isv,CL_isv,V1_isv,Q_isv,V2_isv] = [
    [ 0.1000, 0.0100, 0.0100, 0.0100, 0.0100 ],
    [ 0.0100, 0.0300, -0.0100, 0.0200, 0.0200 ],
    [ 0.0100, -0.0100, 0.0900, 0.0100, 0.0100 ],
    [ 0.0100, 0.0200, 0.0100, 0.0700, 0.0100 ],
    [ 0.0100, 0.0200, 0.0100, 0.0100, 0.0500 ],
]
f[PNOISE] = 0.1500

Outputs

Generated parameter .csv files

Fixed Effects:fx_params.csv (gen)
Random Effects:rx_params.csv (gen)
Model params:mx_params.csv (gen)
State values:sx_params.csv (gen)
Predictions:px_params.csv (gen)
Synthetic Data:synthetic_data.csv (gen)

Plots

Dense sim plots

Alternatively see All dense_sim graph plots

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