One Compartment Model with Absorption and no inter-occasion Variance f[CL_iov]=0¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
Name: | d1cmp_cl_iov_naive |
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Title: | One Compartment Model with Absorption and no inter-occasion Variance f[CL_iov]=0 |
Author: | Wright Dose Ltd |
Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_iov] is not estimated it is set to zero.
Keywords: | one compartment model; dep_one_cmp_cl; iov |
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Input Script: | d1cmp_cl_iov_naive.pyml |
Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.2000
f[CL_iov] = 0.1000
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0000
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 0.3202
f[CL] = 2.5353
f[V] = 20.9735
f[PNOISE_STD] = 0.2297
f[ANOISE_STD] = 0.0975
f[CL_isv] = 0.1396
f[CL_iov] = 0.0000
Plots¶
Comparison¶
True objective value¶
-43.9474
Final fitted objective value¶
-253.7337
Compare Main f[X]¶
Name | Initial | Fitted | True | Prop. Error | Abs. Error |
---|---|---|---|---|---|
f[KA] | 0.5 | 0.32 | 0.3 | 6.73% | 2.02e-02 |
f[CL] | 1 | 2.54 | 3 | 15.49% | 4.65e-01 |
f[V] | 15 | 21 | 20 | 4.87% | 9.73e-01 |
Compare Noise f[X]¶
Name | Initial | Fitted | True | Prop. Error | Abs. Error |
---|---|---|---|---|---|
f[PNOISE_STD] | 0.2 | 0.23 | 0.1 | 129.67% | 1.30e-01 |
f[ANOISE_STD] | 0.2 | 0.0975 | 0.05 | 95.08% | 4.75e-02 |
Compare Variance f[X]¶
Name | Initial | Fitted | True | Prop. Error | Abs. Error |
---|---|---|---|---|---|
f[CL_isv] | 0.01 | 0.14 | 0.2 | 30.21% | 6.04e-02 |