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One Compartment Model with Absorption estimating KA

[Generated automatically as a Tutorial summary]

Model Description

Name:d1cmp_ka_stderr
Title:One Compartment Model with Absorption estimating KA
Author:PoPy for PK/PD
Abstract:
One Compartment Model with Absorption compartment with rate (KA).
Elimination rate parametrised by clearance (CL)
and volume of distribution (V).
Model specification uses incremental flows
Keywords:dep_one_cmp_cl; one compartment model
Input Script:d1cmp_ka_stderr.pyml
Diagram:

Comparison

True objective value

-43.9510

Final fitted objective value

-44.7678

Compare Main f[X]

Name Initial Fitted True Abs. Error Prop. Error
f[KA] 0.3 0.274 0.3 2.61e-02 8.69%

Compare Noise f[X]

No Noise f[X] values to compare.

Compare Variance f[X]

No Variance f[X] values to compare.

Outputs

Fitted f[X] values (after fitting)

f[KA] = 0.2739
f[V] = 18.0030
f[CL] = 3.2389

Generated data .csv file

Synthetic Data:synthetic_data.csv

Inputs

True f[X] values (for simulation)

f[KA] = 0.3000
f[V] = 20.0000
f[CL] = 3.0000

Starting f[X] values (before fitting)

f[KA] = 0.3000
f[V] = 18.0030
f[CL] = 3.2389
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