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Direct PD Model

[Generated automatically as a Generation summary]

Model Description

Name:direct_pd
Title:Direct PD Model
Author:PoPy for PK/PD
Abstract:
A simple direct PD Model, based on the amount of drug in the body.
The amount in the central compartment is determined by K, which has been previously estimated for each individual.
The amount in the central compartment influences the rate of removal of a biomarker (KOUT).
Keywords:pd; one compartment model; direct
Input Script:direct_pd_gen.pyml
Diagram:

Outputs

Population simulated (sim) plots

indOBS_vs_TIME

Generated parameter .csv files

Fixed Effects:fx_params.csv (gen)
Random Effects:rx_params.csv (gen)
Model params:mx_params.csv (gen)
State values:sx_params.csv (gen)
Predictions:px_params.csv (gen)
Observations:synthetic_data.csv (gen)

Inputs

True f[X] values (for simulation)

f[BASE] = 800.0000
f[KOUT] = 0.0300
f[ANOISE] = 0.5000
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