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Full matrix generation full matrix fit

[Generated automatically as a Fitting summary]

Model Description

Name:gen_full_fit_full
Title:Full matrix generation full matrix fit
Author:PoPy for PK/PD
Abstract:
One compartment model with absorption compartment and CL/V parametrisation.
This script uses a full covariance matrix to generate the data and a full covariance matrix to fit.
Keywords:dep_one_cmp_cl; one compartment model; full matrix
Input Script:gen_full_fit_full_fit.pyml
Diagram:

Comparison

Compare Main f[X]

Compare Noise f[X]

Compare Variance f[X]

Variable Name Starting Value Fitted Value Abs Change Prop Change
f[CL_isv] 0.0100 0.1309 0.1209 12.0913
f[CL_isv;V_isv] 0.0010 0.0525 0.0515 51.4634
f[V_isv;CL_isv] 0.0010 0.0525 0.0515 51.4634
f[V_isv] 0.0100 0.1657 0.1557 15.5741

Individual simulated (sim) plots

Alternatively see All simulated_sim graph plots

Population simulated (sim) plots

allOBS_vs_TIME

Outputs

Final objective value

-2120.5340

which required 1.12 iterations and took 1430.58 seconds

Fitted f[X] values (after fitting)

f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv,V_isv] = [
    [ 0.1309, 0.0525 ],
    [ 0.0525, 0.1657 ],
]

Fitted parameter .csv files

Fixed Effects:fx_params.csv (fit)
Random Effects:rx_params.csv (fit)
Model params:mx_params.csv (fit)
State values:sx_params.csv (fit)
Predictions:px_params.csv (fit)
Likelihoods:lx_params.csv (fit)

Inputs

Input Data:cx_obs_params.csv

Starting f[X] values (before fitting)

f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv,V_isv] = [
    [ 0.0100, 0.0010 ],
    [ 0.0010, 0.0100 ],
]
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