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One Compartment Model with Absorption estimating KA and V

[Generated automatically as a Fitting summary]

Inputs

Description

Name:dep_one_cmp_ka_v_stderr
Title:One Compartment Model with Absorption estimating KA and V
Author:Wright Dose Ltd
Abstract:
One Compartment Model with Absorption compartment with rate (KA).
Elimination rate parametrised by clearance (CL)
and volume of distribution (V).
Model specification uses incremental flows
Keywords:dep_one_cmp_cl; one compartment model
Input Script:dep_one_cmp_ka_v_stderr_fit.pyml
Input Data:synthetic_data.csv
Diagram:

Initial fixed effect estimates

f[KA] = 0.3
f[V] = 20
f[CL] = 3.2389

Outputs

Final objective value

-44.767771926

which required N. iterations and took 799.56 seconds

Final fitted fixed effects

f[KA] = 0.27391
f[V] = 18.002
f[CL] = 3.2389

Fitted parameter .csv files

Fixed Effects:fx_params.csv (fit)
Random Effects:rx_params.csv (fit)
Model params:mx_params.csv (fit)
State values:sx_params.csv (fit)
Predictions:px_params.csv (fit)

Plots

Dense sim plots

Alternatively see All dense_sim graph plots

Comparison

Compare Main f[X]

Variable Name Fitted Value Starting Value Prop Change Abs Change
f[KA] 0.273915 0.3 0.0869504 0.0260851
f[V] 18.0023 20 0.0998853 1.99771

Compare Noise f[X]

Compare Variance f[X]

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