One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5¶
[Generated automatically as a Fitting summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_iov_05 |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_isv] true value is 0.5
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | dep_one_cmp_cl_iov_05_fit.pyml |
| Input Data: | synthetic_data.csv |
| Diagram: |
Initial fixed effect estimates¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[PNOISE_STD] = 0.2
f[ANOISE_STD] = 0.2
f[CL_isv] = 0.01
f[CL_iov] = 0.01
Outputs¶
Final fitted fixed effects¶
f[KA] = 1
f[CL] = 1.8485
f[V] = 20.257
f[PNOISE_STD] = 0.21347
f[ANOISE_STD] = 0.047715
f[CL_isv] = 0.27007
f[CL_iov] = 0.008566
Fitted parameter .csv files¶
| Fixed Effects: | fx_params.csv (fit) |
|---|---|
| Random Effects: | rx_params.csv (fit) |
| Model params: | mx_params.csv (fit) |
| State values: | sx_params.csv (fit) |
| Predictions: | px_params.csv (fit) |
Plots¶
Comparison¶
Compare Main f[X]¶
| Variable Name | Fitted Value | Starting Value | Prop Change | Abs Change |
|---|---|---|---|---|
| f[KA] | 1 | 0.5 | 1 | 0.5 |
| f[CL] | 1.84847 | 1 | 0.848469 | 0.848469 |
| f[V] | 20.2568 | 15 | 0.350455 | 5.25682 |
Compare Noise f[X]¶
| Variable Name | Fitted Value | Starting Value | Prop Change | Abs Change |
|---|---|---|---|---|
| f[PNOISE_STD] | 0.213473 | 0.2 | 0.0673627 | 0.0134725 |
| f[ANOISE_STD] | 0.0477148 | 0.2 | 0.761426 | 0.152285 |
Compare Variance f[X]¶
| Variable Name | Fitted Value | Starting Value | Prop Change | Abs Change |
|---|---|---|---|---|
| f[CL_isv] | 0.27007 | 0.01 | 26.007 | 0.26007 |
| f[CL_iov] | 0.00856602 | 0.01 | 0.143398 | 0.00143398 |