- Language: en
Direct PD Model Simultaneous PK/PD Parameter fit¶
[Generated automatically as a Generation summary]
Inputs¶
Description¶
| Name: | direct_pd_simul |
|---|---|
| Title: | Direct PD Model Simultaneous PK/PD Parameter fit |
| Author: | Wright Dose Ltd |
| Abstract: |
A simple direct PD Model, based on the amount of drug in the body. That simultaneously fits PK and PD parameters.
The amount in the central compartment is determined by K, which has been previously estimated for each individual.
The amount in the central compartment influences the rate of removal of a biomarker (KOUT).
| Keywords: | pd; one compartment model; direct |
|---|---|
| Input Script: | direct_pd_simul_gen.pyml |
| Diagram: |
True f[X] values¶
f[CL] = 2.0000
f[V] = 50.0000
f[BASE] = 800.0000
f[KOUT] = 0.0300
f[PK_ANOISE] = 0.5000
f[PD_ANOISE] = 0.3000
Outputs¶
Generated parameter .csv files¶
| Fixed Effects: | fx_params.csv (gen) |
|---|---|
| Random Effects: | rx_params.csv (gen) |
| Model params: | mx_params.csv (gen) |
| State values: | sx_params.csv (gen) |
| Predictions: | px_params.csv (gen) |
| Synthetic Data: | synthetic_data.csv (gen) |
