One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2¶
[Generated automatically as a Fitting summary]
Inputs¶
Description¶
| Name: | d1cmp_cl_iov |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | d1cmp_cl_iov_fit.pyml |
| Input Data: | synthetic_data.csv |
| Diagram: |
Initial fixed effect estimates¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0100
Outputs¶
Final fitted fixed effects¶
f[KA] = 0.3345
f[CL] = 2.5856
f[V] = 20.2051
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0479
f[CL_isv] = 0.1199
f[CL_iov] = 0.0783
Fitted parameter .csv files¶
| Fixed Effects: | fx_params.csv (fit) |
|---|---|
| Random Effects: | rx_params.csv (fit) |
| Model params: | mx_params.csv (fit) |
| State values: | sx_params.csv (fit) |
| Predictions: | px_params.csv (fit) |
Plots¶
Comparison¶
Compare Main f[X]¶
| Variable Name | Starting Value | Fitted Value | Prop Change | Abs Change |
|---|---|---|---|---|
| f[KA] | 0.5000 | 0.3345 | 0.3309 | 0.1655 |
| f[CL] | 1.0000 | 2.5856 | 1.5856 | 1.5856 |
| f[V] | 15.0000 | 20.2051 | 0.3470 | 5.2051 |
Compare Noise f[X]¶
| Variable Name | Starting Value | Fitted Value | Prop Change | Abs Change |
|---|---|---|---|---|
| f[PNOISE_STD] | 0.2000 | 0.1000 | 0.4998 | 0.1000 |
| f[ANOISE_STD] | 0.2000 | 0.0479 | 0.7605 | 0.1521 |
Compare Variance f[X]¶
| Variable Name | Starting Value | Fitted Value | Prop Change | Abs Change |
|---|---|---|---|---|
| f[CL_isv] | 0.0100 | 0.1199 | 10.9948 | 0.1099 |
| f[CL_iov] | 0.0100 | 0.0783 | 6.8312 | 0.0683 |