One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2¶

[Generated automatically as a Tutorial summary]

Model Description¶

Name:	d1cmp_cl_iov
Title:	One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2
Author:	PoPy for PK/PD
Abstract:

Population one Compartment Model with Absorption and Inter-occasion Variance

Keywords:	one compartment model; dep_one_cmp_cl; iov
Input Script:	`d1cmp_cl_iov.pyml`
Diagram:

-358.2450

-363.8118

Name	Initial	Fitted	True	Abs. Error	Prop. Error
f[KA]	0.5	0.335	0.3	3.45e-02	11.51%
f[CL]	1	2.59	3	4.15e-01	13.82%
f[V]	15	20.2	20	2.05e-01	1.03%

Name	Initial	Fitted	True	Abs. Error	Prop. Error
f[PNOISE_STD]	0.2	0.1…	0.1	3.15e-05	0.03%
f[ANOISE_STD]	0.2	0.0479	0.05	2.10e-03	4.20%

Name	Initial	Fitted	True	Abs. Error	Prop. Error
f[CL_isv]	0.01	0.12	0.2	8.01e-02	40.03%
f[CL_iov]	0.01	0.0783	0.1	2.17e-02	21.69%

f[KA] = 0.3345
f[CL] = 2.5855
f[V] = 20.2051
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0479
f[CL_isv] = 0.1199
f[CL_iov] = 0.0783

Synthetic Data:	`synthetic_data.csv`

f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.2000
f[CL_iov] = 0.1000

f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0100