One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2¶

[Generated automatically as a Tutorial summary]

Model Description¶

Name:	d1cmp_cl_iov
Title:	One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2
Author:	PoPy for PK/PD
Abstract:

Population one Compartment Model with Absorption and Inter-occasion Variance

Keywords:	one compartment model; dep_one_cmp_cl; iov
Input Script:	`d1cmp_cl_iov.pyml`
Diagram:

-392.2101

-398.8099

Name	Initial	Fitted	True	Abs. Error	Prop. Error
f[KA]	0.5	0.318	0.3	1.79e-02	5.98%
f[CL]	1	3.33	3	3.33e-01	11.10%
f[V]	15	19.3	20	6.53e-01	3.27%

Name	Initial	Fitted	True	Abs. Error	Prop. Error
f[PNOISE_STD]	0.2	0.0946	0.1	5.42e-03	5.42%
f[ANOISE_STD]	0.2	0.0495	0.05	4.71e-04	0.94%

Name	Initial	Fitted	True	Abs. Error	Prop. Error
f[CL_isv]	0.01	0.146	0.2	5.36e-02	26.82%
f[CL_iov]	0.01	0.0608	0.1	3.92e-02	39.20%

f[KA] = 0.3179
f[CL] = 3.3331
f[V] = 19.3470
f[PNOISE_STD] = 0.0946
f[ANOISE_STD] = 0.0495
f[CL_isv] = 0.1464
f[CL_iov] = 0.0608

Synthetic Data:	`synthetic_data.csv`

f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.2000
f[CL_iov] = 0.1000

f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0100