One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2¶
[Generated automatically as a Fitting summary]
Model Description¶
Name: | d1cmp_cl_iov |
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Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2 |
Author: | PoPy for PK/PD |
Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Keywords: | one compartment model; dep_one_cmp_cl; iov |
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Input Script: | d1cmp_cl_iov_fit.pyml |
Diagram: |
Comparison¶
Compare Main f[X]¶
Variable Name | Starting Value | Fitted Value | Abs Change | Prop Change |
---|---|---|---|---|
f[KA] | 0.5000 | 0.3345 | 0.1655 | 0.3309 |
f[CL] | 1.0000 | 2.5855 | 1.5855 | 1.5855 |
f[V] | 15.0000 | 20.2051 | 5.2051 | 0.3470 |
Compare Noise f[X]¶
Variable Name | Starting Value | Fitted Value | Abs Change | Prop Change |
---|---|---|---|---|
f[PNOISE_STD] | 0.2000 | 0.1000 | 0.1000 | 0.4998 |
f[ANOISE_STD] | 0.2000 | 0.0479 | 0.1521 | 0.7605 |
Compare Variance f[X]¶
Variable Name | Starting Value | Fitted Value | Abs Change | Prop Change |
---|---|---|---|---|
f[CL_isv] | 0.0100 | 0.1199 | 0.1099 | 10.9949 |
f[CL_iov] | 0.0100 | 0.0783 | 0.0683 | 6.8312 |
Population simulated (sim) plots¶
allOBS_vs_TIME |
Outputs¶
Fitted f[X] values (after fitting)¶
f[KA] = 0.3345
f[CL] = 2.5855
f[V] = 20.2051
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0479
f[CL_isv] = 0.1199
f[CL_iov] = 0.0783
Fitted parameter .csv files¶
Fixed Effects: | fx_params.csv (fit) |
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Random Effects: | rx_params.csv (fit) |
Model params: | mx_params.csv (fit) |
State values: | sx_params.csv (fit) |
Predictions: | px_params.csv (fit) |
Likelihoods: | lx_params.csv (fit) |
Inputs¶
Input Data: | cx_obs_params.csv |
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Starting f[X] values (before fitting)¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0100