One Compartment Model with Absorption and no inter-occasion Variance f[CL_iov]=0¶
[Generated automatically as a Tutorial summary]
Model Description¶
Name: | d1cmp_cl_iov_naive |
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Title: | One Compartment Model with Absorption and no inter-occasion Variance f[CL_iov]=0 |
Author: | PoPy for PK/PD |
Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_iov] is not estimated it is set to zero.
Keywords: | one compartment model; dep_one_cmp_cl; iov |
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Input Script: | d1cmp_cl_iov_naive.pyml |
Diagram: |
Comparison¶
True objective value¶
-43.9474
Final fitted objective value¶
-253.7337
Compare Main f[X]¶
Name | Initial | Fitted | True | Abs. Error | Prop. Error |
---|---|---|---|---|---|
f[KA] | 0.5 | 0.32 | 0.3 | 2.02e-02 | 6.74% |
f[CL] | 1 | 2.53 | 3 | 4.65e-01 | 15.50% |
f[V] | 15 | 21 | 20 | 9.76e-01 | 4.88% |
Compare Noise f[X]¶
Name | Initial | Fitted | True | Abs. Error | Prop. Error |
---|---|---|---|---|---|
f[PNOISE_STD] | 0.2 | 0.23 | 0.1 | 1.30e-01 | 129.67% |
f[ANOISE_STD] | 0.2 | 0.0976 | 0.05 | 4.76e-02 | 95.13% |
Compare Variance f[X]¶
Name | Initial | Fitted | True | Abs. Error | Prop. Error |
---|---|---|---|---|---|
f[CL_isv] | 0.01 | 0.14 | 0.2 | 6.05e-02 | 30.25% |
Outputs¶
Fitted f[X] values (after fitting)¶
f[KA] = 0.3202
f[CL] = 2.5349
f[V] = 20.9761
f[PNOISE_STD] = 0.2297
f[ANOISE_STD] = 0.0976
f[CL_isv] = 0.1395
f[CL_iov] = 0.0000
Generated data .csv file¶
Synthetic Data: | synthetic_data.csv |
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Gen and Fit Summaries¶
Inputs¶
True f[X] values (for simulation)¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.2000
f[CL_iov] = 0.1000
Starting f[X] values (before fitting)¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0000