First order absorption model with peripheral compartment¶
[Generated automatically as a Generation summary]
Model Description¶
| Name: | builtin_gen_example |
|---|---|
| Title: | First order absorption model with peripheral compartment |
| Author: | PoPy for PK/PD |
| Abstract: |
A two compartment PK model with bolus dose and
first order absorption, similar to a Nonmem advan4trans4 model.
| Keywords: | generating; pk; advan4; dep_two_cmp; first order |
|---|---|
| Input Script: | builtin_gen_example.pyml |
| Diagram: |
Outputs¶
Population simulated (sim) plots¶
(No population graphs were requested.)
Generated parameter .csv files¶
| Fixed Effects: | fx_params.csv (gen) |
|---|---|
| Random Effects: | rx_params.csv (gen) |
| Model params: | mx_params.csv (gen) |
| State values: | sx_params.csv (gen) |
| Predictions: | px_params.csv (gen) |
| Observations: | synthetic_data.csv (gen) |
Inputs¶
True f[X] values (for simulation)¶
f[KA] = 0.2000
f[CL] = 2.0000
f[V1] = 50.0000
f[Q] = 1.0000
f[V2] = 80.0000
f[KA_isv,CL_isv,V1_isv,Q_isv,V2_isv] = [
[ 0.1000, 0.0100, 0.0100, 0.0100, 0.0100 ],
[ 0.0100, 0.0300, -0.0100, 0.0200, 0.0200 ],
[ 0.0100, -0.0100, 0.0900, 0.0100, 0.0100 ],
[ 0.0100, 0.0200, 0.0100, 0.0700, 0.0100 ],
[ 0.0100, 0.0200, 0.0100, 0.0100, 0.0500 ],
]
f[PNOISE] = 0.1500