One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2¶
[Generated automatically as a Fitting summary]
Model Description¶
Name: | d1cmp_cl_iov |
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Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2 |
Author: | PoPy for PK/PD |
Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Keywords: | one compartment model; dep_one_cmp_cl; iov |
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Input Script: | d1cmp_cl_iov_fit.pyml |
Diagram: |
Comparison¶
Compare Main f[X]¶
Variable Name | Starting Value | Fitted Value | Abs Change | Prop Change |
---|---|---|---|---|
f[KA] | 0.5000 | 0.3179 | 0.1821 | 0.3641 |
f[CL] | 1.0000 | 3.3331 | 2.3331 | 2.3331 |
f[V] | 15.0000 | 19.3470 | 4.3470 | 0.2898 |
Compare Noise f[X]¶
Variable Name | Starting Value | Fitted Value | Abs Change | Prop Change |
---|---|---|---|---|
f[PNOISE_STD] | 0.2000 | 0.0946 | 0.1054 | 0.5271 |
f[ANOISE_STD] | 0.2000 | 0.0495 | 0.1505 | 0.7524 |
Compare Variance f[X]¶
Variable Name | Starting Value | Fitted Value | Abs Change | Prop Change |
---|---|---|---|---|
f[CL_isv] | 0.0100 | 0.1464 | 0.1364 | 13.6369 |
f[CL_iov] | 0.0100 | 0.0608 | 0.0508 | 5.0802 |
Population simulated (sim) plots¶
allOBS_vs_TIME |
Outputs¶
Fitted f[X] values (after fitting)¶
f[KA] = 0.3179
f[CL] = 3.3331
f[V] = 19.3470
f[PNOISE_STD] = 0.0946
f[ANOISE_STD] = 0.0495
f[CL_isv] = 0.1464
f[CL_iov] = 0.0608
Fitted parameter .csv files¶
Fixed Effects: | fx_params.csv (fit) |
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Random Effects: | rx_params.csv (fit) |
Model params: | mx_params.csv (fit) |
State values: | sx_params.csv (fit) |
Predictions: | px_params.csv (fit) |
Likelihoods: | lx_params.csv (fit) |
Inputs¶
Input Data: | cx_obs_params.csv |
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Starting f[X] values (before fitting)¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0100