One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2¶
[Generated automatically as a Tutorial summary]
Model Description¶
Name: | d1cmp_cl_isv |
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Title: | One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2 |
Author: | PoPy for PK/PD |
Abstract: |
Population one Compartment Model with Absorption and Inter-subject Variance
Keywords: | one compartment model; dep_one_cmp_cl |
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Input Script: | d1cmp_cl_isv.pyml |
Diagram: |
Comparison¶
True objective value¶
-417.7570
Final fitted objective value¶
-430.9290
Compare Main f[X]¶
Name | Initial | Fitted | True | Abs. Error | Prop. Error |
---|---|---|---|---|---|
f[KA] | 0.5 | 0.28 | 0.3 | 1.98e-02 | 6.60% |
f[CL] | 1 | 3.23 | 3 | 2.27e-01 | 7.58% |
f[V] | 15 | 19.8 | 20 | 1.61e-01 | 0.80% |
Compare Noise f[X]¶
Name | Initial | Fitted | True | Abs. Error | Prop. Error |
---|---|---|---|---|---|
f[PNOISE_STD] | 0.2 | 0.0809 | 0.1 | 1.91e-02 | 19.05% |
f[ANOISE_STD] | 0.2 | 0.0373 | 0.05 | 1.27e-02 | 25.37% |
Compare Variance f[X]¶
Name | Initial | Fitted | True | Abs. Error | Prop. Error |
---|---|---|---|---|---|
f[CL_isv] | 0.01 | 0.177 | 0.2 | 2.34e-02 | 11.72% |
Outputs¶
Fitted f[X] values (after fitting)¶
f[KA] = 0.2802
f[CL] = 3.2273
f[V] = 19.8391
f[PNOISE_STD] = 0.0809
f[ANOISE_STD] = 0.0373
f[CL_isv] = 0.1766
Generated data .csv file¶
Synthetic Data: | synthetic_data.csv |
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Gen and Fit Summaries¶
Inputs¶
True f[X] values (for simulation)¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.2000
Starting f[X] values (before fitting)¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100