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First order absorption model with peripheral compartment

[Generated automatically as a Generation summary]

Model Description

Name:

builtin_gen_example

Title:

First order absorption model with peripheral compartment

Author:

PoPy for PK/PD

Abstract:

A two compartment PK model with bolus dose and
first order absorption, similar to a Nonmem advan4trans4 model.
Keywords:

generating; pk; advan4; dep_two_cmp; first order

Input Script:

builtin_gen_example.pyml

Diagram:

Outputs

Individual simulated (sim) plots

Alternatively see All simulated_sim graph plots

Population simulated (sim) plots

(No population graphs were requested.)

Generated parameter .csv files

Fixed Effects:

fx_params.csv (gen)

Random Effects:

rx_params.csv (gen)

Model params:

mx_params.csv (gen)

State values:

sx_params.csv (gen)

Predictions:

px_params.csv (gen)

Observations:

synthetic_data.csv (gen)

Inputs

True f[X] values (for simulation)

f[KA] = 0.2000
f[CL] = 2.0000
f[V1] = 50.0000
f[Q] = 1.0000
f[V2] = 80.0000
f[KA_isv,CL_isv,V1_isv,Q_isv,V2_isv] = [
    [ 0.1000, 0.0100, 0.0100, 0.0100, 0.0100 ],
    [ 0.0100, 0.0300, -0.0100, 0.0200, 0.0200 ],
    [ 0.0100, -0.0100, 0.0900, 0.0100, 0.0100 ],
    [ 0.0100, 0.0200, 0.0100, 0.0700, 0.0100 ],
    [ 0.0100, 0.0200, 0.0100, 0.0100, 0.0500 ],
]
f[PNOISE] = 0.1500
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