One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_isv |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-subject Variance
| Keywords: | one compartment model; dep_one_cmp_cl |
|---|---|
| Input Script: | dep_one_cmp_cl_isv.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[PNOISE_STD] = 0.1
f[ANOISE_STD] = 0.05
f[CL_isv] = 0.2
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[PNOISE_STD] = 0.2
f[ANOISE_STD] = 0.2
f[CL_isv] = 0.01
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1
f[CL] = 2.4567
f[V] = 22.048
f[PNOISE_STD] = 0.23467
f[ANOISE_STD] = 0.03752
f[CL_isv] = 0.1284
Plots¶
Comparison¶
True objective value¶
-362.688042983
Final fitted objective value¶
-311.99664349
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 2.46 | 3 | 18.11% | 5.43e-01 |
| f[V] | 15 | 22 | 20 | 10.24% | 2.05e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.235 | 0.1 | 134.67% | 1.35e-01 |
| f[ANOISE_STD] | 0.2 | 0.0375 | 0.05 | 24.96% | 1.25e-02 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.128 | 0.2 | 35.80% | 7.16e-02 |