One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_isv |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-subject Variance
| Keywords: | one compartment model; dep_one_cmp_cl |
|---|---|
| Input Script: | dep_one_cmp_cl_isv.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[PNOISE_STD] = 0.1
f[ANOISE_STD] = 0.05
f[CL_isv] = 0.2
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[PNOISE_STD] = 0.2
f[ANOISE_STD] = 0.2
f[CL_isv] = 0.01
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1
f[CL] = 2.4482
f[V] = 21.931
f[PNOISE_STD] = 0.23417
f[ANOISE_STD] = 0.037484
f[CL_isv] = 0.12828
Plots¶
Comparison¶
True objective value¶
-362.687685887
Final fitted objective value¶
-311.993879624
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 2.45 | 3 | 18.39% | 5.52e-01 |
| f[V] | 15 | 21.9 | 20 | 9.65% | 1.93e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.234 | 0.1 | 134.17% | 1.34e-01 |
| f[ANOISE_STD] | 0.2 | 0.0375 | 0.05 | 25.03% | 1.25e-02 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.128 | 0.2 | 35.86% | 7.17e-02 |