One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_isv |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-subject Variance
| Keywords: | one compartment model; dep_one_cmp_cl |
|---|---|
| Input Script: | dep_one_cmp_cl_isv.pyml |
| Diagram: |
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.2000
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1.0000
f[CL] = 2.5556
f[V] = 22.1555
f[PNOISE_STD] = 0.2308
f[ANOISE_STD] = 0.0372
f[CL_isv] = 0.1279
Plots¶
Comparison¶
True objective value¶
-362.6880
Final fitted objective value¶
-311.6031
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 2.56 | 3 | 14.81% | 4.44e-01 |
| f[V] | 15 | 22.2 | 20 | 10.78% | 2.16e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.231 | 0.1 | 130.77% | 1.31e-01 |
| f[ANOISE_STD] | 0.2 | 0.0372 | 0.05 | 25.68% | 1.28e-02 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.128 | 0.2 | 36.05% | 7.21e-02 |