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One Compartment Model with Absorption estimating KA, V and CL

[Generated automatically as a Tutorial summary]

Inputs

Description

Name:d1cmp_ka_v_cl_stderr
Title:One Compartment Model with Absorption estimating KA, V and CL
Author:Wright Dose Ltd
Abstract:
One Compartment Model with Absorption compartment with rate (KA).
Elimination rate parametrised by clearance (CL)
and volume of distribution (V).
Model specification uses incremental flows
Keywords:dep_one_cmp_cl; one compartment model
Input Script:d1cmp_ka_v_cl_stderr.pyml
Diagram:

True f[X] values

f[KA] = 0.3000
f[V] = 20.0000
f[CL] = 3.0000

Starting f[X] values

f[KA] = 0.3000
f[V] = 20.0000
f[CL] = 3.0000

Outputs

Generated data .csv file

Synthetic Data:synthetic_data.csv

Fitted f[X] values

f[KA] = 0.2738
f[V] = 17.9983
f[CL] = 3.2389

Plots

Dense comp plots

Alternatively see All dense_comp graph plots

Comparison

True objective value

-42.7757

Final fitted objective value

-44.7678

Compare Main f[X]

Name Initial Fitted True Prop. Error Abs. Error
f[KA] 0.3 0.274 0.3 8.72% 2.62e-02
f[V] 20 18 20 10.01% 2.00e+00
f[CL] 3 3.24 3 7.96% 2.39e-01

Compare Noise f[X]

No Noise f[X] values to compare.

Compare Variance f[X]

No Variance f[X] values to compare.

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