One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_iov |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | dep_one_cmp_cl_iov.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[PNOISE_STD] = 0.1
f[ANOISE_STD] = 0.05
f[CL_isv] = 0.2
f[CL_iov] = 0.1
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[PNOISE_STD] = 0.2
f[ANOISE_STD] = 0.2
f[CL_isv] = 0.01
f[CL_iov] = 0.01
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1
f[CL] = 2.2203
f[V] = 20.724
f[PNOISE_STD] = 0.21306
f[ANOISE_STD] = 0.052026
f[CL_isv] = 0.072757
f[CL_iov] = 0.1003
Plots¶
Comparison¶
True objective value¶
-344.393565165
Final fitted objective value¶
-276.234739885
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 2.22 | 3 | 25.99% | 7.80e-01 |
| f[V] | 15 | 20.7 | 20 | 3.62% | 7.24e-01 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.213 | 0.1 | 113.06% | 1.13e-01 |
| f[ANOISE_STD] | 0.2 | 0.052 | 0.05 | 4.05% | 2.03e-03 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.0728 | 0.2 | 63.62% | 1.27e-01 |
| f[CL_iov] | 0.01 | 0.1… | 0.1 | 0.30% | 2.97e-04 |