One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_iov |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | dep_one_cmp_cl_iov.pyml |
| Diagram: |
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.2000
f[CL_iov] = 0.1000
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0100
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 0.2711
f[CL] = 2.4007
f[V] = 18.3926
f[PNOISE_STD] = 0.0935
f[ANOISE_STD] = 0.0487
f[CL_isv] = 0.0829
f[CL_iov] = 0.1073
Plots¶
Comparison¶
True objective value¶
-344.3936
Final fitted objective value¶
-353.3355
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 0.271 | 0.3 | 9.62% | 2.89e-02 |
| f[CL] | 1 | 2.4 | 3 | 19.98% | 5.99e-01 |
| f[V] | 15 | 18.4 | 20 | 8.04% | 1.61e+00 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.0935 | 0.1 | 6.51% | 6.51e-03 |
| f[ANOISE_STD] | 0.2 | 0.0487 | 0.05 | 2.64% | 1.32e-03 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.0829 | 0.2 | 58.57% | 1.17e-01 |
| f[CL_iov] | 0.01 | 0.107 | 0.1 | 7.32% | 7.32e-03 |