One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_iov |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.2 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | dep_one_cmp_cl_iov.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[PNOISE_STD] = 0.1
f[ANOISE_STD] = 0.05
f[CL_isv] = 0.2
f[CL_iov] = 0.1
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[PNOISE_STD] = 0.2
f[ANOISE_STD] = 0.2
f[CL_isv] = 0.01
f[CL_iov] = 0.01
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1
f[CL] = 2.211
f[V] = 20.54
f[PNOISE_STD] = 0.2123
f[ANOISE_STD] = 0.05187
f[CL_isv] = 0.073326
f[CL_iov] = 0.10083
Plots¶
Comparison¶
True objective value¶
-344.39339052
Final fitted objective value¶
-276.187185145
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 2.21 | 3 | 26.30% | 7.89e-01 |
| f[V] | 15 | 20.5 | 20 | 2.70% | 5.40e-01 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.212 | 0.1 | 112.30% | 1.12e-01 |
| f[ANOISE_STD] | 0.2 | 0.0519 | 0.05 | 3.74% | 1.87e-03 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.0733 | 0.2 | 63.34% | 1.27e-01 |
| f[CL_iov] | 0.01 | 0.101 | 0.1 | 0.83% | 8.26e-04 |