One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_iov_05 |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_isv] true value is 0.5
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | dep_one_cmp_cl_iov_05.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[PNOISE_STD] = 0.1
f[ANOISE_STD] = 0.05
f[CL_isv] = 0.5
f[CL_iov] = 0.01
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[PNOISE_STD] = 0.2
f[ANOISE_STD] = 0.2
f[CL_isv] = 0.01
f[CL_iov] = 0.01
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1
f[CL] = 1.8513
f[V] = 20.269
f[PNOISE_STD] = 0.21367
f[ANOISE_STD] = 0.047704
f[CL_isv] = 0.26995
f[CL_iov] = 0.0085567
Plots¶
Comparison¶
True objective value¶
-352.854755698
Final fitted objective value¶
-276.581051572
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 1.85 | 3 | 38.29% | 1.15e+00 |
| f[V] | 15 | 20.3 | 20 | 1.35% | 2.69e-01 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.214 | 0.1 | 113.67% | 1.14e-01 |
| f[ANOISE_STD] | 0.2 | 0.0477 | 0.05 | 4.59% | 2.30e-03 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.27 | 0.5 | 46.01% | 2.30e-01 |
| f[CL_iov] | 0.01 | 0.00856 | 0.01 | 14.43% | 1.44e-03 |