One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_iov_05 |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_isv] true value is 0.5
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | dep_one_cmp_cl_iov_05.pyml |
| Diagram: |
Failed to create compartment diagram
True f[X] values¶
f[KA] = 0.3
f[CL] = 3
f[V] = 20
f[PNOISE_STD] = 0.1
f[ANOISE_STD] = 0.05
f[CL_isv] = 0.5
f[CL_iov] = 0.01
Starting f[X] values¶
f[KA] = 0.5
f[CL] = 1
f[V] = 15
f[PNOISE_STD] = 0.2
f[ANOISE_STD] = 0.2
f[CL_isv] = 0.01
f[CL_iov] = 0.01
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1
f[CL] = 1.8485
f[V] = 20.257
f[PNOISE_STD] = 0.21347
f[ANOISE_STD] = 0.047715
f[CL_isv] = 0.27007
f[CL_iov] = 0.008566
Plots¶
Comparison¶
True objective value¶
-352.854494995
Final fitted objective value¶
-276.597501804
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 1.85 | 3 | 38.38% | 1.15e+00 |
| f[V] | 15 | 20.3 | 20 | 1.28% | 2.57e-01 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.213 | 0.1 | 113.47% | 1.13e-01 |
| f[ANOISE_STD] | 0.2 | 0.0477 | 0.05 | 4.57% | 2.29e-03 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.27 | 0.5 | 45.99% | 2.30e-01 |
| f[CL_iov] | 0.01 | 0.00857 | 0.01 | 14.34% | 1.43e-03 |