One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_iov_05 |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_isv] true value is 0.5
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | dep_one_cmp_cl_iov_05.pyml |
| Diagram: |
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.5000
f[CL_iov] = 0.0100
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0100
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1.0000
f[CL] = 1.8764
f[V] = 19.6864
f[PNOISE_STD] = 0.2153
f[ANOISE_STD] = 0.0468
f[CL_isv] = 0.2677
f[CL_iov] = 0.0084
Plots¶
Comparison¶
True objective value¶
-352.8545
Final fitted objective value¶
-276.4412
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 1.88 | 3 | 37.45% | 1.12e+00 |
| f[V] | 15 | 19.7 | 20 | 1.57% | 3.14e-01 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.215 | 0.1 | 115.30% | 1.15e-01 |
| f[ANOISE_STD] | 0.2 | 0.0468 | 0.05 | 6.41% | 3.21e-03 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.268 | 0.5 | 46.46% | 2.32e-01 |
| f[CL_iov] | 0.01 | 0.00843 | 0.01 | 15.67% | 1.57e-03 |