One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
Name: | dep_one_cmp_cl_iov_05 |
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Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5 |
Author: | Wright Dose Ltd |
Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_isv] true value is 0.5
Keywords: | one compartment model; dep_one_cmp_cl; iov |
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Input Script: | dep_one_cmp_cl_iov_05.pyml |
Diagram: |
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.5000
f[CL_iov] = 0.0100
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0100
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1.0000
f[CL] = 1.9217
f[V] = 20.2630
f[PNOISE_STD] = 0.2081
f[ANOISE_STD] = 0.0480
f[CL_isv] = 0.2662
f[CL_iov] = 0.0084
Plots¶
Comparison¶
True objective value¶
-352.8550
Final fitted objective value¶
-276.7600
Compare Main f[X]¶
Name | Initial | Fitted | True | Prop. Error | Abs. Error |
---|---|---|---|---|---|
f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
f[CL] | 1 | 1.92 | 3 | 35.94% | 1.08e+00 |
f[V] | 15 | 20.3 | 20 | 1.32% | 2.63e-01 |
Compare Noise f[X]¶
Name | Initial | Fitted | True | Prop. Error | Abs. Error |
---|---|---|---|---|---|
f[PNOISE_STD] | 0.2 | 0.208 | 0.1 | 108.09% | 1.08e-01 |
f[ANOISE_STD] | 0.2 | 0.048 | 0.05 | 3.97% | 1.98e-03 |
Compare Variance f[X]¶
Name | Initial | Fitted | True | Prop. Error | Abs. Error |
---|---|---|---|---|---|
f[CL_isv] | 0.01 | 0.266 | 0.5 | 46.77% | 2.34e-01 |
f[CL_iov] | 0.01 | 0.00845 | 0.01 | 15.50% | 1.55e-03 |