One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5¶
[Generated automatically as a Tutorial summary]
Inputs¶
Description¶
| Name: | dep_one_cmp_cl_iov_05 |
|---|---|
| Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5 |
| Author: | Wright Dose Ltd |
| Abstract: |
Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_isv] true value is 0.5
| Keywords: | one compartment model; dep_one_cmp_cl; iov |
|---|---|
| Input Script: | dep_one_cmp_cl_iov_05.pyml |
| Diagram: |
True f[X] values¶
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[PNOISE_STD] = 0.1000
f[ANOISE_STD] = 0.0500
f[CL_isv] = 0.5000
f[CL_iov] = 0.0100
Starting f[X] values¶
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[PNOISE_STD] = 0.2000
f[ANOISE_STD] = 0.2000
f[CL_isv] = 0.0100
f[CL_iov] = 0.0100
Outputs¶
Generating and Fitting Summaries¶
Fitted f[X] values¶
f[KA] = 1.0000
f[CL] = 1.9129
f[V] = 20.2481
f[PNOISE_STD] = 0.2087
f[ANOISE_STD] = 0.0483
f[CL_isv] = 0.2392
f[CL_iov] = 0.0075
Plots¶
Comparison¶
True objective value¶
-352.8547
Final fitted objective value¶
-276.7916
Compare Main f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01 |
| f[CL] | 1 | 1.91 | 3 | 36.24% | 1.09e+00 |
| f[V] | 15 | 20.2 | 20 | 1.24% | 2.48e-01 |
Compare Noise f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[PNOISE_STD] | 0.2 | 0.209 | 0.1 | 108.70% | 1.09e-01 |
| f[ANOISE_STD] | 0.2 | 0.0483 | 0.05 | 3.32% | 1.66e-03 |
Compare Variance f[X]¶
| Name | Initial | Fitted | True | Prop. Error | Abs. Error |
|---|---|---|---|---|---|
| f[CL_isv] | 0.01 | 0.239 | 0.5 | 52.16% | 2.61e-01 |
| f[CL_iov] | 0.01 | 0.00749 | 0.01 | 25.14% | 2.51e-03 |